Article
A cloned human germ cell tumor-derived cell line differentiating in culture.
International journal of cancer - 31 Aug 1998
Tienari J, Reima I, Larramendy M L, Knuutila S, von Boguslawsky K, Kaartinen M, Virtanen I, Lehtonen E
Abstract excerpt
We have derived a clonal cell line (HGCT-1) from a lymph node metastasis of a primary testicular germ cell tumor (GCT). The tumor was negative for the embryonal carcinoma (EC) cell marker BerH2 but positive for vimentin, cytokeratin (CK) and desmin. Comparative genomic hybridization (CGH) reveale...
Topics
- Animals
- Cell Culture Techniques
- Cell Differentiation
- Chromosome Aberrations
- Clone Cells
- Desmin
- Germinoma
- Humans
- Immunohistochemistry
- Immunosuppression Therapy
- Keratins
- Lymphatic Metastasis
- Male
- Mesoderm
- Phenotype
- Rats
- Testicular Neoplasms
- Transplantation, Heterologous