Article
Microarray-based identification of a novel Streptococcus pneumoniae regulon controlled by an autoinduced peptide.
Journal of bacteriology - 1 Sept 2000
de Saizieu A, Gardès C, Flint N, Wagner C, Kamber M, Mitchell T J, Keck W, Amrein K E, Lange R
Abstract excerpt
We have identified in the Streptococcus pneumoniae genome sequence a two-component system (TCS13, Blp [bacteriocin-like peptide]) which is closely related to quorum-sensing systems regulating cell density-dependent phenotypes such as the development of genetic competence or the production of antimicrobial peptides in lactic acid bacteria. In this study we present evidence that TCS13 is a peptide-sensing system...
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