Article
Investigating the Streptococcus sinensis competence regulon through a combination of transcriptome analysis and phenotypic evaluation.
Microbiology (Reading, England) - 1 Oct 2022
Brennan Alec A, Harrington Anthony, Guo Mingzhe, Renshaw Clay P, Tillett Richard L, Miura Pedro, Tal-Gan Yftah
Abstract excerpt
Streptococcus sinensis is a recently identified member of the Mitis group of streptococci. This species has been associated with infective endocarditis; however its mechanisms of pathogenesis and virulence are not fully understood. This study aimed to investigate the influence of the competence-stimulating peptide (CSP) and the competence regulon quorum-sensing circuitry (ComABCDE) on subsequent gene...
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