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Article

A New Role for Polyketides

18 Aug 2000

Abstract excerpt

A toxic determinant of the human skin disease the Buruli ulcer, which is caused by Mycobacterium ulcerans, has been identified for the first time as containing two polyketides. The novel structures of these twelve-membered macrolides (one of which is shown) reveal an unusual biosynthesis, in which two type 1 polyketide synthases (PKS) have to be involved. There is also evidence that the polyketide toxin might...

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Identifiers

PMID: 11027985
DOI: 10.1002/1521-3773(20000818)39:16<2847::aid-anie2847>3.0.co;2-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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