Article
The glycosyl phosphatidylinositol anchor of human T-cadherin binds lipoproteins.
Biochemical and biophysical research communications - 5 Oct 2000
Niermann T, Kern F, Erne P, Resink T
Abstract excerpt
T-cadherin (T-cad) is a Ca(2+)-dependent cell adhesion glycoprotein bound to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor. T-cad expressed on vascular smooth muscle cells (SMC) binds lipoproteins on blot. To analyze the molecular basis for the interaction of T-cad with lipoproteins we expressed recombinant human T-cad in HEK293 cells. Whereas membrane-bound T-cad from SMC and T-cad...
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