Article
Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2011
Gin Peter, Beigneux Anne P, Voss Constance, Davies Brandon S J, Beckstead Jennifer A, Ryan Robert O, Bensadoun André, Fong Loren G, Young Stephen G
Abstract excerpt
OBJECTIVE: To define the ability of GPIHBP1 to bind other lipase family members and other apolipoproteins (apos) and lipoproteins. METHODS AND RESULTS: GPIHBP1, a GPI-anchored lymphocyte antigen (Ly)6 protein of capillary endothelial cells, binds lipoprotein lipase (LPL) avidly, but its ability to bind related lipase family members has never been evaluated. As judged by cell-based and cell-free binding assays,...
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