Article
The ATPase domain of hsp70 possesses a unique binding specificity for 3'-sulfogalactolipids.
The Journal of biological chemistry - 5 Jan 2001
Mamelak D, Lingwood C
Abstract excerpt
The region(s) of hsp70 critical for sulfogalactolipid (SGL) recognition has been defined through deletion analysis and site-directed mutagenesis. Truncated polymerase chain reaction products of hsp70 generated N-terminal fragments of 43, 35, 29, and 22 kDa. The C terminus substrate-binding domain (28 kDa) was also expressed. The N-terminal ATPase domain (rP43) shared the binding specificity of hsp70, because only...
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