Article
A Wnt signaling system that specifies two patterns of cell migration in C. elegans.
Molecular cell - 1 Nov 1999
Whangbo J, Kenyon C
Abstract excerpt
In C. elegans, a bilateral pair of neuroblasts, QL and QR, give rise to cells that migrate in opposite directions along the anteroposterior (A/P) body axis. QL and its descendants migrate posteriorly whereas QR and its descendants migrate anteriorly. We find that a Wnt family member, EGL-20, acts in a dose-dependent manner to specify these opposite migratory behaviors. High levels of EGL-20 promote posterior...
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