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Article

A clinical feature associated with polymorphisms of the TNF region in Japanese patients with palmoplantar pustulosis.

Human immunology - 1 May 2003

Hashigucci Kazuhiro, Niizeki Hironori, Naruse Taeko, Ota Masao, Inamoto Nobuko, Nishikawa Takeji, Inoko Hidetoshi

Abstract excerpt

We investigated the association of polymorphisms in the tumor necrosis factor (TNF) microsatellite as well as the promoter region of the TNFA gene and the TNFB gene with palmoplantar pustulosis (PPP). In order to clarify the heterogeneity of this disease, we performed a tonsillar provocation test on 78 patients and divided them into two groups according to the results; provocation positive (PP; n = 38) and...

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PMID: 12691703
DOI: 10.1016/s0198-8859(03)00034-x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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