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Article

Telomere fusions caused by mutating the terminal region of telomeric DNA.

Proceedings of the National Academy of Sciences of the United States of America - 10 Oct 2000

McEachern M J, Iyer S, Fulton T B, Blackburn E H

Abstract excerpt

Mutations in the template region of a telomerase RNA gene can lead to the corresponding sequence alterations appearing in newly synthesized telomeric repeats. We analyzed a set of mutations in the template region of the telomerase RNA gene (TER1) of the budding yeast Kluyveromyces lactis that were predicted to lead to synthesis of mutant telomeric repeats with disrupted binding of the telomeric protein Rap1p. We...

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Identifiers

PMID: 11016977
DOI: 10.1073/pnas.210388397
PMCID: PMC17213

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Telomere fusions caused by mutating the terminal region of telomeric DNA.PMID 11016977Read ↗

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