Article

Anti-inflammatory and anti-fibrotic effects of topical pan-JAK inhibitor in a chronic graft-versus- host disease model mouse

2024-04-19

Abstract excerpt

<title>Abstract</title> <p>Systemic administration of Janus kinase (JAK) inhibitors is effective in treating chronic graft-versus-host disease (cGVHD) but is associated with side effects. Topical drug administration is an effective approach in minimizing these effects. We aimed to demonstrate the efficacy of topical delgocitinib administration in a cGVHD mouse model. Allogenic bone-marrow transplantation (BMT) wa...

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Literature Corpus work: e1dca27e-0fb2-5e31-8526-46f11991582b
DOI: 10.21203/rs.3.rs-4252479/v1

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