Article
On the differences between maximum likelihood and regression interval mapping in the analysis of quantitative trait loci.
Genetics - 1 Oct 2000
Kao C H
Abstract excerpt
The differences between maximum-likelihood (ML) and regression (REG) interval mapping in the analysis of quantitative trait loci (QTL) are investigated analytically and numerically by simulation. The analytical investigation is based on the comparison of the solution sets of the ML and REG methods in the estimation of QTL parameters. Their differences are found to relate to the similarity between the conditional...
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