Article
The full EM algorithm for the MLEs of QTL effects and positions and their estimated variances in multiple-interval mapping.
Biometrics - 1 Jun 2005
Chen Zehua
Abstract excerpt
The advent of complete genetic linkage maps of DNA markers has made systematic studies of mapping quantitative trait loci (QTL) in experimental organisms feasible. The method of multiple-interval mapping provides an appropriate way for mapping QTL using genetic markers. However, efficient algorithms for the computation involved remain to be developed. In this article, a full EM algorithm for the simultaneous...
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