Article
Generalized linear model for interval mapping of quantitative trait loci.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Jun 2010
Xu Shizhong, Hu Zhiqiu
Abstract excerpt
We developed a generalized linear model of QTL mapping for discrete traits in line crossing experiments. Parameter estimation was achieved using two different algorithms, a mixture model-based EM (expectation-maximization) algorithm and a GEE (generalized estimating equation) algorithm under a heterogeneous residual variance model. The methods were developed using ordinal data, binary data, binomial data and...
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