General formulas for obtaining the MLEs and the asymptotic variance-covariance matrix in mapping quantitative trait loci when using the EM algorithm.

Article

General formulas for obtaining the MLEs and the asymptotic variance-covariance matrix in mapping quantitative trait loci when using the EM algorithm.

Biometrics - 1 Jun 1997

Kao C H, Zeng Z B

Abstract excerpt

We present in this paper general formulas for deriving the maximum likelihood estimates and the asymptotic variance-covariance matrix of the positions and effects of quantitative trait loci (QTLs) in a finite normal mixture model when the EM algorithm is used for mapping QTLs. The general formula...

Topics

Algorithms
Analysis of Variance
Animals
Biometry
Chromosome Mapping
Computer Simulation
Female
Genetic Markers
Genotype
Likelihood Functions
Male
Models, Genetic
Models, Statistical

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