Article
Cross-referencing radiation hybrid data to the recombination map: lessons from mouse chromosome 18.
Genomics - 1 Oct 2000
Rowe L B, Barter M E, Eppig J T
Abstract excerpt
We are building a framework map of known-order anchor markers between the mouse T31 radiation hybrid (RH) panel and the recombination map based on The Jackson Laboratory (TJL) interspecific backcross panels using the established genetic order to evaluate and strengthen the RH results. In making this map comparison, we have elucidated several problems inherent in RH mapping and minimized these by careful attention...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Chromosomes
- Cricetinae
- Crosses, Genetic
- DNA
- DNA Primers
- Female
- Hybrid Cells
- Male
- Mice
- Mice, Inbred C57BL
- Microsatellite Repeats
- Muridae
- Polymerase Chain Reaction
- Radiation Hybrid Mapping
- Recombination, Genetic
