Article
A new standard genetic map for the laboratory mouse.
Genetics - 1 Aug 2009
Cox Allison, Ackert-Bicknell Cheryl L, Dumont Beth L, Ding Yueming, Bell Jordana Tzenova, Brockmann Gudrun A, Wergedal Jon E, Bult Carol, Paigen Beverly, Flint Jonathan, Tsaih Shirng-Wern, Churchill Gary A, Broman Karl W
Abstract excerpt
Genetic maps provide a means to estimate the probability of the co-inheritance of linked loci as they are transmitted across generations in both experimental and natural populations. However, in the age of whole-genome sequences, physical distances measured in base pairs of DNA provide the standard coordinates for navigating the myriad features of genomes. Although genetic and physical maps are colinear, there...
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