Article
Minisatellite mutation frequency in human sperm following radiotherapy.
Mutation research - 20 Sept 2000
May C A, Tamaki K, Neumann R, Wilson G, Zagars G, Pollack A, Dubrova Y E, Jeffreys A J, Meistrich M L
Abstract excerpt
Screening pedigrees for inherited minisatellite length changes provides an efficient means of monitoring repeat DNA instability but has given rise to apparently contradictory results regarding the effects of radiation on the human germline. To explore this further in individuals with known radiation doses and to potentially gain information on the timing of mutation induction, we have used an extremely sensitive...
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