Article
Mini-and microsatellite mutations in children from Chernobyl accident cleanup workers.
Mutation research - 11 Apr 2004
Slebos Robbert J C, Little Ruth E, Umbach David M, Antipkin Yurij, Zadaorozhnaja Tamara D, Mendel Nikola A, Sommer Courtney A, Conway Kathleen, Parrish Eloise, Gulino Sara, Taylor Jack A
Abstract excerpt
Knowledge about possible genotoxic effects of low-dose radiation on the human germline is limited and relies primarily on extrapolations from high-dose exposures. To test whether ionizing radiation can cause paternal genetic mutations that are transmitted to offspring, we enrolled families of 88 Chernobyl cleanup workers exposed to ionizing radiation. We analyzed DNA isolated from lymphocytes for mutations via...
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