Article
Radiation induction of germline mutation at a hypervariable mouse minisatellite locus.
International journal of radiation biology - 1 May 1994
Sadamoto S, Suzuki S, Kamiya K, Kominami R, Dohi K, Niwa O
Abstract excerpt
Paternal 60Co gamma-irradiation was tested for the induction of germline mutation at the mouse hypervariable minisatellite locus, Ms6hm. Male C3H/HeN mice were exposed to 3 Gy 60Co gamma-ray and mated with C57BL/6N females. Matings were made at 1-7, 15-21 and 71-77 days post-treatment to test spe...
Topics
- Animals
- DNA, Satellite
- Female
- Genetic Variation
- Heterozygote
- Immunoglobulin Variable Region
- Litter Size
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mutation
- Repetitive Sequences, Nucleic Acid
- Spermatids
- Spermatogonia
- Spermatozoa