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Article

Selective expression of lysyl oxidase (LOX) in the stromal reactions of broncho-pulmonary carcinomas.

Histology and histopathology - 1 Oct 2000

Peyrol S, Galateau-Salle F, Raccurt M, Gleyzal C, Sommer P

Abstract excerpt

Lysyl oxidase (LOX) is the extracellular enzyme that initiates the main pathway of collagen and elastin cross-linking. LOX has also been correlated with the ras recision gene, a putative tumour suppressor isolated from revertants of ras-transformed fibroblasts. The present study investigates the...

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Source

Identifiers

PMID: 11005237
DOI: 10.14670/HH-15.1127

Genes

LOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11005237-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Selective expression of lysyl oxidase (LOX) in the stromal reactions of broncho-pulmonary carcinomas.PMID 11005237Read ↗

The lysyl oxidase LOX is absent in basal and squamous cell carcinomas and its knockdown induces an invading phenotype in a skin equivalent model.Semantic proximity Read ↗

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The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer.Semantic proximity Read ↗

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Targeting the lysyl oxidases in tumour desmoplasiaSemantic proximity Read ↗

Differential expression of the LOX family genes in human colorectal adenocarcinomasSemantic proximity Read ↗

Regulation of elastin promoter by lysyl oxidase and growth factors: cross control of lysyl oxidase on TGF-beta1 effects.Semantic proximity Read ↗

The complete derived amino acid sequence of human lysyl oxidase and assignment of the gene to chromosome 5 (extensive sequence homology with the murine ras recision gene).Semantic proximity Read ↗

Partial restoration of pre-transformation levels of lysyl oxidase and transin mRNAs in phenotypic ras revertants.Semantic proximity Read ↗

Wound repair-induced expression of a stromelysins is associated with the acquisition of a mesenchymal phenotype in human respiratory epithelial cells.Semantic proximity Read ↗

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