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Article

p27<sup>Kip1</sup> is an inducer of intestinal epithelial cell differentiation

1 Oct 2000

Abstract excerpt

Constant renewal of the intestinal epithelium is a highly coordinated process that has been subject to intense investigation, but its regulatory mechanisms are still essentially unknown. In this study, we have demonstrated that forced expression of the cyclin-dependent kinase inhibitors (CKIs) p27(Kip1) and p21(Cip1/WAF1) in human intestinal epithelial cells led to expression of differentiation markers at both...

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Identifiers

PMID: 11003585
DOI: 10.1152/ajpcell.2000.279.4.c1045

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