Article
Wilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA.
Proceedings of the National Academy of Sciences of the United States of America - 14 Nov 2006
Horiuchi Keiko, Umetani Michihisa, Minami Takashi, Okayama Hiroto, Takada Shinji, Yamamoto Masayuki, Aburatani Hiroyuki, Reid Patrick C, Housman David E, Hamakubo Takao, Kodama Tatsuhiko
Abstract excerpt
Wilms' tumor 1-associating protein (WTAP) has been reported to be a ubiquitously expressed nuclear protein. Although a relation to splicing factors has been postulated, its actual physiological function still remains to be elucidated. To investigate the role of WTAP, we generated WTAP-knockout mi...
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