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Article

C242T polymorphism of the p22 phox gene is not associated with peripheral arterial occlusive disease.

Atherosclerosis - 1 Sept 2000

Renner W, Schallmoser K, Gallippi P, Krauss C, Toplak H, Wascher T C, Pilger E

Abstract excerpt

Formation of reactive oxygen metabolites is vital for the microbicidal activity of phagocytes. As an unwanted side effect, these metabolites may contribute to oxidative stress in the vasculature and thus lead to arteriosclerosis. p22 phox, a component of the NADH/NADPH oxidase in phagocytes and vascular smooth muscle cells, is essential for production of reactive oxygen metabolites. Recently, a C/T polymorphism...

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Source

Identifiers

PMID: 10996353
DOI: 10.1016/s0021-9150(99)00448-7

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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