Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship of the C242T p22phox gene polymorphism to angiographic coronary artery disease and endothelial function.

American journal of medical genetics - 3 Sept 1999

Li A, Prasad A, Mincemoyer R, Satorius C, Epstein N, Finkel T, Quyyumi A A

Abstract excerpt

Patients with coronary artery disease (CAD) have impaired endothelial function in part due to an increase in vascular oxidant stress. p22phox, an essential component of the NADPH oxidase, is thought to play a critical role in the generation of superoxide anions in the vessel wall. The C242T polym...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcholine
Share to Coronary Angiography
Share to Coronary Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelium, Vascular

Share to Hemodynamics

Share to NADPH Dehydrogenase

Share to NADPH Oxidases

Share to Nitroprusside

Source

Identifiers

PMID: 10440830
DOI: 10.1002/(sici)1096-8628(19990903)86:1<57::aid-ajmg11>3.0.co;2-r

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10440830-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship of the C242T p22phox gene polymorphism to angiographic coronary artery disease and endothelial function.PMID 10440830Read ↗

The A640G and C242T p22(phox) polymorphisms in patients with coronary artery disease.Semantic proximity Read ↗

The p22phox C242T gene polymorphism is associated with a reduced risk of angiographically verified coronary artery disease in a high-risk Finnish Caucasian population. The Finnish Cardiovascular Study.Semantic proximity Read ↗

Relationship of the p22phox (CYBA) gene polymorphism C242T with risk of coronary artery disease: a meta-analysis.Semantic proximity Read ↗

Association of nicotinamide adenine dinucleotide phosphate oxidase p22phox gene 549C>T polymorphism with coronary artery disease.Semantic proximity Read ↗

Association of p22phox gene C242T polymorphism with coronary artery disease: a meta-analysis.Semantic proximity Read ↗

C242T polymorphism of the NADPH oxidase p22PHOX gene and its association with endothelial dysfunction in asymptomatic individuals with essential systemic hypertension.Semantic proximity Read ↗

C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population.Semantic proximity Read ↗

NADH/NADPH oxidase <i>p22</i><i>phox</i> C242T polymorphism and coronary artery disease in the Australian populationSemantic proximity Read ↗

C242T polymorphism in CYBA gene (p22phox) and risk of coronary artery disease in a population of Caucasian Italians.Semantic proximity Read ↗

Genetic factors associated with endothelial dysfunction affect the early onset of coronary artery disease in Korean males.Semantic proximity Read ↗

The C242T p22phox polymorphism and endothelium-dependent vasodilation in subjects with hypercholesterolaemia.Semantic proximity Read ↗

C242T polymorphism of NADPH oxidase p22phox and recurrence of cardiovascular events in coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.