Article
UVB-irradiated T-cells undergoing apoptosis lose L-selectin by metalloprotese-mediated shedding.
International journal of radiation biology - 1 Sept 2000
Kern P M, Keilholz L, Forster C, Stach C, Beyer T D, Gaipl U S, Kalden J R, Hallmann R, Herrmann M
Abstract excerpt
PURPOSE: L-selectin (CD62L) is a prerequisite for leucocyte adhesion to endothelial cells of blood vessels and consequently for transmigration. Its expression on the cell surface therefore regulates the ability of lymphocytes to enter lymph nodes, to re-enter blood vessels or to invade tissues at sites of inflammation. The aim of this study was to determine the expression of CD62L on apoptotic lymphocytes after...
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