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Article

Parkinson disease: analysis of mitochondrial DNA in monozygotic twins.

Neurogenetics - 1 Mar 2000

Kösel S, Grasbon-Frodl E M, Hagenah J M, Graeber M B, Vieregge P

Abstract excerpt

We have sequenced all mitochondrial complex I and tRNA genes in five pairs of monozygotic twins with a longitudinal diagnosis of idiopathic Parkinson disease (PD). At the time of molecular genetic analysis, four of the pairs were discordant for PD. Five novel homoplasmic sequence variants, including two missense mutations (ND2 4924 G/A, ND3 10192 C/T), were detected in mitochondrial genes of complex I in four of...

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Source

Identifiers

PMID: 10983718
DOI: 10.1007/pl00022973

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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