Article
The genetic jigsaw of inflammatory bowel disease.
Gut - 1 May 2002
Watts D A, Satsangi J
Abstract excerpt
Following a prolonged period of relative inertia, real progress has been made in the past few years in understanding the pathogenesis of the chronic inflammatory bowel diseases, Crohn's disease and ulcerative colitis. Clinical experience, epidemiological studies, and molecular genetics have provided strong evidence that both genetic and environmental factors are important in disease pathogenesis, and...
Topics
- Antibodies, Monoclonal
- Chromosomes, Human, Pair 12
- Colitis, Ulcerative
- Crohn Disease
- Gastrointestinal Agents
- Genes, MHC Class I
- Genes, MHC Class II
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Humans