Article
Association of a uteroglobin polymorphism with rate of progression in patients with IgA nephropathy.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Sept 2000
Szelestei T, Bähring S, Kovács T, Vas T, Salamon C, Busjahn A, Luft F C, Nagy J
Abstract excerpt
Uteroglobin gene-disrupted mice develop a nephritis very similar to immunoglobulin A (IgA) nephropathy. Megsin codes for a protein overexpressed in mesangium in patients with IgA nephropathy. Both are candidate genes that might have variants associated with an accelerated progression in patients with IgA nephropathy. We performed an association study of patients with IgA nephropathy and matching control subjects...
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