Article
Analysis of a uteroglobin gene polymorphism in childhood Henoch-Schonlein purpura.
Pediatric nephrology (Berlin, Germany) - 1 Jun 2006
Eisenstein Eli M, Choi Moonsuk
Abstract excerpt
Uteroglobin (UG) is a pleiotropic protein with anti-inflammatory properties. Mice rendered genetically incapable of expressing UG develop a form of renal disease that closely resembles human IgA nephropathy (IgAN). Furthermore, a single nucleotide polymorphism in the UG gene (A38G) has been associated with rapid progression of human IgAN. We examined whether the A38G polymorphism is associated with childhood...
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