Article
An immortalized septal cell line that expresses trkA mRNA in response to basic fibroblast growth factor.
Neurochemistry international - 1 Oct 1997
Miyasaka N, Matsuoka I, Kurihara K
Abstract excerpt
Cells dissociated from embryonic rat septum were transfected with SV40 large T antigen gene by the calcium phosphate precipitation method. One of the cloned lines (EG6) had a flat morphology and expressed nestin gene, a marker of neural stem cells. Upon stimulation with basic fibroblast growth factor (bFGF), morphological changes of EG6 cells were induced, e.g. shrinkage of cell body and extension of neuritic...
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