Article
Comparative analysis of amino acid sequences from envelope proteins isolated from different hepatitis C virus variants: possible role of conservative and variable regions.
Journal of viral hepatitis - 1 Sept 2000
Sobolev B N, Poroikov V V, Olenina L V, Kolesanova E F, Archakov A I
Abstract excerpt
Sequences of the E1 and E2 envelope proteins of hepatitis C virus (HCV) (827 non-identical items) were collected from available sources and aligned. Analysis of the alignment identified regions with different sequence variability. It was found that 33% and 50% of positions within E1 and E2, respectively, were highly conservative. Such conservation can be considered as the minimum for maintaining stability of the...
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