Article
High-resolution analysis of ethanol-induced locomotor stimulation in Drosophila.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Dec 2002
Wolf Fred W, Rodan Aylin R, Tsai Linus T-Y, Heberlein Ulrike
Abstract excerpt
Understanding how ethanol influences behavior is key to deciphering the mechanisms of ethanol action and alcoholism. In mammals, low doses of ethanol stimulate locomotion, whereas high doses depress it. The acute stimulant effect of ethanol has been proposed to be a manifestation of its rewarding effects. In Drosophila, ethanol exposure transiently potentiates locomotor activity in a biphasic dose- and...
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