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Article

Examination of the transcription factor NtcA-binding motif by in vitro selection of DNA sequences from a random library.

Journal of molecular biology - 25 Aug 2000

Jiang F, Wisén S, Widersten M, Bergman B, Mannervik B

Abstract excerpt

A recursive in vitro selection among random DNA sequences was used for analysis of the cyanobacterial transcription factor NtcA-binding motifs. An eight-base palindromic sequence, TGTA-(N(8))-TACA, was found to be the optimal NtcA-binding sequence. The more divergent the binding sequences, compared to this consensus sequence, the lower the NtcA affinity. The second and third bases in each four-nucleotide half of...

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Identifiers

PMID: 10966785
DOI: 10.1006/jmbi.2000.4000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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