Article
Molecular cloning of the critical region for glomerulopathy with fibronectin deposits (GFND) and evaluation of candidate genes.
Genomics - 1 Sept 2000
Vollmer M, Kremer M, Ruf R, Miot S, Nothwang H G, Wirth J, Otto E, Krapf R, Hildebrandt F
Abstract excerpt
Glomerulopathy with fibronectin deposits (GFND, MIM 601894) is an autosomal dominant kidney disease that leads to terminal renal failure at a median age of 47 years. It represents a distinct entity of membranoproliferative glomerulonephritis (MPGN) type III and is characterized by the unique feature of massive glomerular deposits of fibronectin. We have recently localized a gene locus for GFND to human chromosome...
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