Article
Association study of a functional serotonin transporter gene polymorphism with schizophrenia, psychopathology and clozapine response.
Schizophrenia research - 1 Sept 2000
Tsai S J, Hong C J, Yu Y W, Lin C H, Song H L, Lai H C, Yang K H
Abstract excerpt
Serotonin is implicated in the pathogenesis of schizophrenia. Following serotonin release, the serotonin transporter (5-HTT) is the major determinant of serotonin inactivation. The present study tested the hypothesis that a biallelic polymorphism in the 5' regulatory region of the 5-HTT gene (5-HTTLPR) confers susceptibility to schizophrenia, association with the clinical manifestations of schizophrenia or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
