Article
Investigation of major genetic polymorphisms in the Renin-Angiotensin-aldosterone system in subjects with young-onset hypertension selected by a targeted-screening system at university.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2007
Miyama Noriyuki, Hasegawa Yoko, Suzuki Michiko, Hida Wataru, Kazama Itsuro, Hatano Ryo, Sanada Satoru, Arata Tomoaki, Michimata Mari, Sato Akira, Satomi Susumu, Matsubara Mitsunobu
Abstract excerpt
Although polymorphisms in renin-angiotensin-aldosterone (RAA) system genes for angiotensinogen (AGT M235T), angiotensin-converting enzyme (ACE I/D), angiotensin II type 1 receptor (AT1 A/C1166), and aldosterone synthase (CYP11B2-344T/C) have been major targets for genetic investigation in association with essential hypertension (EH), the influence of these genetic factors is still to be determined. Because...
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