Article
Angiotensinogen gene variation and hypertension in a cohort study in Japanese.
Journal of epidemiology - 1 May 2001
Kishimoto T, Suyama A, Igarashi A, Osaki Y, Okamoto M, Yamamoto T, Nanba E, Kurosawa Y, Fukumoto S
Abstract excerpt
Many recent case-control studies have suggested a significant relationship between M235T (the substitution of threonine for methionine at position 235 codon) polymorphism of the angiotensinogen (AGT) gene and hypertension. To investigate whether the M235T polymorphism of AGT gene affects the incidence of hypertension, a retrospective cohort study was performed among Japanese workers. The subjects were Japanese...
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