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Article

Combined effects of adeno-associated virus vector and a herpes simplex virus mutant as neoplastic therapy.

Journal of surgical oncology - 1 Jul 2000

Kasuya H, Mizuno M, Yoshida J, Nishiyama Y, Nomoto S, Nakao A

Abstract excerpt

BACKGROUND AND OBJECTIVES: Although surgical therapy for pancreatic cancer has not been successful, new gene therapies, such as adeno-associated virus (AAV) vectors hold promise for treating cancer. However, expression of AAV vectors alone is insufficient for adequate effects in vivo for cancer therapy. We describe a novel therapy using the combined herpes simplex virus-ICP6 deletion mutant (ICP6delta) and AAV...

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Source

Identifiers

PMID: 10951421
DOI: 10.1002/1096-9098(200007)74:3<214::aid-jso12>3.0.co;2-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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