Article
Differential suppression of the tumorigenicity of HeLa and SiHa cells by adeno-associated virus.
British journal of cancer - 1 Jun 1996
Su P F, Wu F Y
Abstract excerpt
Adeno-associated virus (AAV) is well known for suppression of oncogenesis in rodents, but its inhibitory effects on human carcinoma are less well understood. We report the differential ability of AAV to inhibit the tumorigenicity of two human cervical carcinoma cell lines. The wild-type AAV-2 DNA carried by a pSV2Neo vector was transfected into HeLa cells, which contain 50 copies of human papillomavirus type 18...
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