Evolvability of an RNA virus is determined by its mutational neighbourhood.

doi:10.1038/35020564

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Article

Evolvability of an RNA virus is determined by its mutational neighbourhood.

Nature - 10 Aug 2000

Burch C L, Chao L

Abstract excerpt

The ubiquity of mechanisms that generate genetic variation has spurred arguments that evolvability, the ability to generate adaptive variation, has itself evolved in response to natural selection. The high mutation rate of RNA viruses is postulated to be an adaptation for evolvability, but the pa...

Topics

Bacteriophage phi 6
Directed Molecular Evolution
Mutation

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