Article
Behavioural changes produced by transgenic overexpression of gamma2L and gamma2S subunits of the GABAA receptor.
The European journal of neuroscience - 1 Jul 2000
Wick M J, Radcliffe R A, Bowers B J, Mascia M P, Lüscher B, Harris R A, Wehner J M
Abstract excerpt
Transgenic mice overexpressing either the mouse gamma2L or gamma2S subunit of the GABAA receptor were generated in a C57BL/6 J x DBA/2 J mixed background and expanded into transgenic lines. Transgenic mice and littermate controls were analysed with respect to altered behaviour indicative of anxiety, motor activity and acute effects of benzodiazepines and alcohol, as well as with regard to altered responses to...
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