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Significance of Mutations in the Androgen Receptor Gene in Males with Idiopathic Infertility1

1 Aug 2000

Abstract excerpt

Abnormal human spermatogenesis is caused by a variety of genetic and acquired conditions. Because spermatogenesis is dependent on androgens, some males may have a minimal form of androgen insensitivity that does not inhibit virilization but impairs fertility. This has lead us to investigate the possibility of abnormalities in the androgen receptor (AR) gene in a large cohort of males suffering from infertility of...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 10946887
DOI: 10.1210/jcem.85.8.6713

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