Article
Analysis of the transactivation domain of the androgen receptor in patients with male infertility.
Clinical genetics - 1 Sept 1998
Wang Q, Ghadessy F J, Yong E L
Abstract excerpt
Genetic defects of the human androgen receptor (AR) can cause a wide spectrum of androgen insensitivity syndromes (AIS) in XY individuals ranging from phenotypic females, to defective spermatogenesis in otherwise normal males. We screened the non-polymorphic regions of exon 1, transactivation domain (TAD), of the AR gene in 153 subjects with varying degrees of defective spermatogenesis of unknown aetiology, and...
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