Male infertility and androgen receptor gene mutations: clinical features and identification of seven novel mutations.

doi:10.1111/j.1365-2265.2006.02635.x

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Male infertility and androgen receptor gene mutations: clinical features and identification of seven novel mutations.

Clinical endocrinology - 1 Nov 2006

Ferlin Alberto, Vinanzi Cinzia, Garolla Andrea, Selice Riccardo, Zuccarello Daniela, Cazzadore Carla, Foresta Carlo

Abstract excerpt

OBJECTIVE: Androgens and a functioning androgen receptor (AR) are essential for development and maintenance of the male phenotype and spermatogenesis. Consistent with this, mutations in the AR gene cause a variety of defects related to androgen insensitivity, ranging from complete feminization to phenotypic males with infertility. The aim of his study was to analyse the prevalence of AR gene mutations in male...

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Male infertility and androgen receptor gene mutations: clinical features and identification of seven novel mutations.

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