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Article

Androgen receptor polymorphisms and mutations in male infertility.

Journal of endocrinological investigation - 1 Oct 2000

Yong E L, Lim L S, Wang Q, Mifsud A, Lim J, Ong Y C, Sim K S

Abstract excerpt

Normal spermatogenesis depends on a sequential cascade of genetic events triggered by factors encoded by sex chromosomes. To determine the contribution of genetic aberrations to male infertility, the X-linked androgen receptor (AR) gene was examined for mutations and polymorphisms in a large cohort of infertile men. Genetic screening of over 400 patients and controls showed that defects in the AR gene lead to the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Receptors, Androgen

Share to Repetitive Sequences, Nucleic Acid

Share to Sexual Differentiation and Disorders

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Source

Identifiers

PMID: 11079451
DOI: 10.1007/BF03343778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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