Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in selenoprotein genes increase risk of colorectal cancer.

Carcinogenesis - 1 Jun 2010

Méplan Catherine, Hughes David J, Pardini Barbara, Naccarati Alessio, Soucek Pavel, Vodickova Ludmila, Hlavatá Ivona, Vrána David, Vodicka Pavel, Hesketh John E

Abstract excerpt

Low selenium (Se) status correlates with increased risk of colorectal cancer (CRC). Since Se exerts its biological roles through the selenoproteins, genetic variations in selenoprotein genes may influence susceptibility to CRC. This study analysed 12 single-nucleotide polymorphisms (SNPs) in sele...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Case-Control Studies
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GPX1 gene

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Selenoproteins

Source

Identifiers

PMID: 20378690
DOI: 10.1093/carcin/bgq076

Genes

GPX4
SOD2
TXNRD2
GPX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20378690-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in selenoprotein genes increase risk of colorectal cancer.PMID 20378690Read ↗

The influence of selenium and selenoprotein gene variants on colorectal cancer risk.Semantic proximity Read ↗

Association of the selenoprotein 15-kDa (SEP15) polymorphisms with cancer risk: a meta-analysis.Semantic proximity Read ↗

Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer.Semantic proximity Read ↗

The Associations of Selenoprotein Genetic Variants with the Risks of Colorectal Adenoma and Colorectal Cancer: Case-Control Studies in Irish and Czech Populations.Semantic proximity Read ↗

Selenium and cancer: a story that should not be forgotten-insights from genomics.Semantic proximity Read ↗

Molecular mechanisms by which selenoproteins affect cancer risk and progression.Semantic proximity Read ↗

The link between selenium and chemoprevention: a case for selenoproteins.Semantic proximity Read ↗

Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma.Semantic proximity Read ↗

Effects of selenium status and polymorphisms in selenoprotein genes on prostate cancer risk in a prospective study of European men.Semantic proximity Read ↗

The SELS rs34713741 Polymorphism Is Associated with Susceptibility to Colorectal Cancer and Gastric Cancer: A Meta-Analysis.Semantic proximity Read ↗

Serum selenium, genetic variation in selenoenzymes, and risk of colorectal cancer: primary analysis from the Women's Health Initiative Observational Study and meta-analysis.Semantic proximity Read ↗

Distribution and functional consequences of nucleotide polymorphisms in the 3'-untranslated region of the human Sep15 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.