Article
Level of selenoprotein transcripts in peripheral leukocytes of patients with bladder cancer and healthy individuals.
Clinical chemistry and laboratory medicine - 1 Jan 2009
Reszka Edyta, Gromadzinska Jolanta, Jablonska Ewa, Wasowicz Wojciech, Jablonowski Zbigniew, Sosnowski Marek
Abstract excerpt
BACKGROUND: Low concentrations of selenium (Se) in humans have been associated with risk of cancer. Selenoprotein mRNAs can potentially be regulated by Se status. METHODS: Se status, GPx1 Pro198Leu and Sep15 1125G/A genetic polymorphism and human (h)GPx1, hGPx3, hSep15 and hSeP1 transcript levels in peripheral leukocytes of 33 males with bladder cancer and 47 healthy male controls were analysed. RESULTS: All the...
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