Article
Mannose-binding lectin and susceptibility to infection in Chinese patients with systemic lupus erythematosus.
The Journal of rheumatology - 1 Jun 2007
Mok Mo Yin, Ip W K Eddie, Lau Chak Sing, Lo Yi, Wong Wilfred H S, Lau Yu Lung
Abstract excerpt
OBJECTIVE: To test the hypothesis that low serum mannose-binding lectin (MBL) levels, as a result of the single-nucleotide polymorphisms in the promoter region (-221 X/Y) and exon 1 (codon 54 A/B) of the MBL2 gene, predispose to infection in Chinese patients with systemic lupus erythematosus (SLE). METHODS: Two hundred forty-five patients with SLE were prospectively followed for the development of major infective...
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