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Article

Identification of a two-component regulatory system involved in antimicrobial peptide resistance in Streptococcus pneumoniae

8 Apr 2022

Abstract excerpt

Two-component regulatory systems (TCS) are among the most widespread mechanisms that bacteria use to sense and respond to environmental changes. In the human pathogen Streptococcus pneumoniae, a total of 13 TCS have been identified and many of them have been linked to pathogenicity. Notably, TCS01 strongly contributes to pneumococcal virulence in several infection models. However, it remains one of the least...

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PMID: 35395062
DOI: 10.1371/journal.ppat.1010458

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